Genome editing is a group of technologies that provide the ability to change an organism’s DNA. It allows genetic material to be added, removed, or altered at particular locations in the genome. The 2012 discovery of a new genome-editing method, widely known as CRISPR-Cas system, has triggered a revolutionary wave in the field of biotechnology. The 2020 Nobel Prize in Chemistry was awarded for CRISPR genome-editing. CRISPR technology has enormously higher precision, efficiency, strong specificity and effectiveness when compared to previously known genomeediting methods. In a very short span, CRISPR technology has demonstrated its near-unlimited potential and solution for therapeutics, diagnostics, medicine, and agriculture.